Lugar: San Juan y San Vicente

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PROGRAMME

9:00-10:00 Registration

10:00-10:10 Welcome speech

10:10-13:25 SESSION 1 Nucleic acids as drugs and biomarkers (chair Ramón Eritja)

10:10-10:55 Applying the chemist's toolbox to gene silencing and gene editing technologies. Masad Damha (invited speaker)

10:55-11:15 DNA-based nanoscaffolds as carrier of 5-fluoro-2'-deoxyuridine oligomers in colorectal cancer therapy. Carme Fàbrega

11:15-11:45 COFFEE BREAK

11:45-12:05 Inhibition of replicative stress genes WEE1 and CHK1 using Polypurine Reverse Hoogsteen Hairpins. Eva Aubets

12:05-12:25 MicroRNA sensors based on gold nanoparticles functionalized with oligonucleotides. Catarina Coutinho

12:25-12:45 FANA Oligonucleotide-Based Therapy Targeting MicroRNAs in Myotonic Dystrophy. Arturo López

12:45-13:05 Activation of transposable elements as biomarkers of neuroimmune disease. Elisa Oltra

13:05-13:25 2shRNA: A promising approach for multi-targeted treatment of cancer. Montserrat Terrazas

13:30-15:00 LUNCH

15:00-17:55 SESSION 2 Nucleic acids as targets (chair Federico Gago)

15:00-15:45 Modulation of RNA Biology in Human Disease with Small Molecules. Razvan Nutiu (invited speaker)

15:45-16:05 G-quadruplex DNA as target in cancer and parasites: ligands based on carbohydrate naphthalene diimide conjugates. Juan Carlos Morales

16:05-16:25 A multidimensional approach to combat ALS. Miguel Garavís

16:25 - 16:55 COFFEE BREAK

16:55-17:15 Discovering novel HIV inhibitors that interfere with RRE-Rev complex formation. Cristina Medina-Trillo

17:15-17:35 Structural studies of i-motifs/duplex junctions and their complexes with small ligands. Israel Serrano

17:35-17:55 (F)uridylated Peptides Linked to Vpg1 of Foot-and-Mouth Disease Virus (FMDV): Design, Synthesis and X-Ray Crystallography of the Complexes with FMDV RNA-dependent RNA polymerase. Sonia de Castro

17:55-18:25 Discussion and election of site for XIII RANN

21:00-23:00 CONFERENCE DINNER